A summary of MRC Impact Acceleration projects MRC IAA Round 1 (2022) Dr Kevin MyantDevelopment of a Kras splicing inhibitor for treatment of colorectal cancerDr Douglas GibsonRapid non-invasive diagnosis of endometriosis using circulating biomarkersDr Grant MairClinical development of a tool for estimating onset time of ischaemic stroke from a CT scanDr Vanessa Smer BarettoNovel AI-enabled chemical design platform for diseases of unmet needProfessor Elizabeth PattonAccelerating the preclinical development of ROS-generating suicide inhibitors for cancer treatmentProfessor David FerenbachStratifying Chronic Kidney Disease patient risk to enable precision medicine approachesProfessor Jonathan Fallowfield Evaluating extracellular vesicles as antifibrotics for the treatment of liver fibrosisDr Yunjie YangDevelopment of perceptive soft surgical robotics MRC IAA Round 2 (2023) Professor Tim Aitman Cell-free DNA as a biomarker of acute aortic syndromeProfessor Andrew BakerEngineering cardiac trophic recombinant adeno-associated virus vectorsProfessor Sara BrownHit-to-lead optimisation for a novel eczema targetProfessor Francesca Mutapi Developing and evaluating a prototype lateral flow test for schistosomiasis infection Dr Ashita SinghTargeting novel enzyme targets to overcome treatment resistance in glioblastoma multiformeProfessor Jose Vazquez-BolandPeptide-based precision anti-infectives for prophylaxis and treatment of foodborne listeriosisDr Qiang WangRapid and precise profiling of tissue biomarker expressions using label-free autofluorescence lifetime imagesMRC IAA Round 3 (2024) Dr David Baird Validation of urinary prognostic biomarkers for chronic kidney diseaseDr Milly LoDevelopment of a novel seizure detection tool for acute careDr Lucy WhitakerTotal body PET-CT for the diagnosis of endometriosisMRC IAA Round 4 (2025) Professor Andy BakerClinical evaluation of differentiated pluripotent stem cell-derived extracellular vesicles for therapeutic angiogenesisDr Dimitrios DoudesisArtificial Intelligence for the diagnosis of acute pulmonary embolism in the Emergency DepartmentProfessor Nick GilbertMonoclonal antibodies targeting the SARS-CoV-2 as a new approach to COVID-19 treatmentDr Dave HanleyStrain-free shape sensing for robotic endoscopyDr Varsha JainDevelopment of a novel uterine actuator for magnetic resonance elastography (MRE) to enhance diagnostic accuracy in women’s healthProfessor Keisuke KajiDeveloping a GMP-compatible culture condition for precursors of chemically expanded hepatocytes as a cell-based therapyProfessor Norbert RadacsiAdvanced 3D-bioprinted Grafts for Bypass Surgeries This article was published on 2024-09-09